Endometriosis clinical trials in Spain (2026)
14 endometriosis trials that are recruiting or about to recruit list at least one site in Spain: 12 from the US registry (ClinicalTrials.gov) and 2 from the EU registry (CTIS). 2 are industry-sponsored.
By phase
Phase 3/4: 1, Phase 1: 1, N/A (non-drug): 6, Observational: 6
Lead sponsors
Hospital Universitari de Bellvitge (1) · Swiss GO Trial Group (1) · Aesculap AG (1) · University of Valencia (1) · Francisco Algaba Chueca (1) · Hospital Universitari Vall d'Hebron Research Institute (1)
Open endometriosis trials with a site in Spain
Newest registry update first. Every ID links to the official record. "est." marks the sponsor's estimated date. A trial registered in both systems may appear twice.
| ID | Title | Lead sponsor | Phase | Status | Primary completion | Enrolment | Site countries |
|---|---|---|---|---|---|---|---|
| NCT06955221 ClinicalTrials.gov | Effect of Alcohol Sclerotherapy on Pelvic Pain and Quality of Life in Women With Ovarian Endometriosis | Hospital Universitari de Bellvitge | N/A (non-drug) | Recruiting | 31 Dec 2026 (est.) | 288 | Spain |
| NCT07397715 ClinicalTrials.gov | Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical Symptoms | Swiss GO Trial Group | Observational | Recruiting | 1 Feb 2028 (est.) | 1,000 | Belgium, Poland, Spain, Switzerland |
| NCT06024109 ClinicalTrials.gov | Performance of SYMMCORA® vs. V-Loc® Suture Material in Patients Undergoing Laparoscopic Total Hysterectomy | Aesculap AG | Observational | Recruiting | Jan 2027 (est.) | 132 | Germany, Spain |
| NCT06212349 ClinicalTrials.gov | Therapeutic-educational Physiotherapy on Pain, Physical-functionality and Quality of Life in Women With Endometriosis. | University of Valencia | N/A (non-drug) | Recruiting | 9 Sep 2027 (est.) | 62 | Spain |
| NCT07578480 ClinicalTrials.gov | MEN-ENDO: Menstrual Stem Cells in Endometriosis | Francisco Algaba Chueca | Observational | Recruiting | Oct 2027 (est.) | 40 | Spain |
| NCT07519343 ClinicalTrials.gov | Migraine and Endometriosis: The FEMININE Study | Hospital Universitari Vall d'Hebron Research Institute | Observational | Not yet recruiting | 1 Jun 2028 (est.) | 150 | Spain |
| NCT06795243 ClinicalTrials.gov | Efficacy of Physical Therapy Treatment in Endometriosis and Its Relationship to Adherence Rates. | University of Seville | N/A (non-drug) | Recruiting | 31 May 2026 (est.) | 32 | Spain |
| NCT06876376 ClinicalTrials.gov | Intraoperative Ultrasound in Bowel Deep Endometriosis | Fundacion Dexeus | Observational | Recruiting | Feb 2027 (est.) | 200 | Spain |
| 2025-521026-15-00 EU CTIS | Personalized Treatment for Endometriosis: A Study on the Safety and Kinetics of Dienogest in Women with Different Gene Variants | Fundacion Para La Investigacion Biomedica Del Hospital Universitario La Princesa | Phase 1 | Authorised, recruiting | — | — | Spain |
| NCT07393958 ClinicalTrials.gov | Impact of Food Supplementation on Quality of Life in Patients With Endometriosis and Pelvic Pain. | Arafarma Group, S.A. | N/A (non-drug) | Recruiting | 1 Aug 2026 (est.) | 60 | Spain |
| NCT07282990 ClinicalTrials.gov | Evolution of Endometriosis Lesions Followed by Ultrasound and Quality of Life of Patients: Factors That Influence Disease Progression in a Prospective Cohort | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Observational | Not yet recruiting | May 2028 (est.) | 100 | Spain |
| NCT07270393 ClinicalTrials.gov | Study of the Influence of the Mediterranean Diet on the Quality of Life of Patients With Endometriosis. | Biogipuzkoa Health Research Institute | N/A (non-drug) | Not yet recruiting | 1 Dec 2026 (est.) | 104 | Spain |
| 2025-522812-18-00 EU CTIS | CARESS Study: Cabergoline for the Reduction of Endometriosis Symptoms and Lesion Size | Hospital Clinico San Carlos | Phase 3/4 | Authorised, recruitment pending | — | — | Spain |
| NCT06209346 ClinicalTrials.gov | Multimodal Physiotherapy Based on Tele-rehabilitation in Chronic Pelvic Pain Associated With Endometriosis | University of Alcala | N/A (non-drug) | Recruiting | 17 Jan 2025 (est.) | 66 | Spain |
Endometriosis trials in other countries: UK · France · Italy · Netherlands · US
Other conditions in Spain: Menopause
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