{
 "pulled_utc": "2026-10-21T12:27:48+00:00",
 "ct_records": 1442,
 "ctis_records": 18,
 "excluded_extra": 7,
 "dropped_by_site_filter": 729,
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   16
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  [
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   167
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 ],
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 "with_sites": 242,
 "geo": {
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  "EU (27 countries)": 67,
  "United Kingdom": 13,
  "Ireland": 1,
  "Elsewhere only": 76
 },
 "ireland_open": [
  {
   "id": "NCT07417228",
   "url": "https://clinicaltrials.gov/study/NCT07417228",
   "title": "The Impact of Concurrent Training on Women Experiencing Symptoms of Menopause",
   "sponsor": "University College Dublin"
  }
 ],
 "ireland_ever": 6,
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  [
   "Spain",
   16
  ],
  [
   "Italy",
   9
  ],
  [
   "France",
   8
  ],
  [
   "Denmark",
   7
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  [
   "Sweden",
   5
  ],
  [
   "Germany",
   4
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 ],
 "top_countries": [
  [
   "United States",
   86
  ],
  [
   "Turkey (T\u00fcrkiye)",
   24
  ],
  [
   "Spain",
   16
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  [
   "United Kingdom",
   13
  ],
  [
   "Canada",
   12
  ],
  [
   "Italy",
   9
  ],
  [
   "France",
   8
  ],
  [
   "Egypt",
   8
  ]
 ],
 "by_sponsor_type": [
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  [
   "LycoRed Ltd.",
   1
  ],
  [
   "BTL Industries Ltd.",
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  [
   "Cuerpos Serranos S.L.",
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  ],
  [
   "Nutrition 21, Inc.",
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  ],
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  [
   "Samphire Group, Inc.",
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  ],
  [
   "Apple Inc.",
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  ],
  [
   "Corium Innovations, Inc.",
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  ],
  [
   "ApexCPG LLC",
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  [
   "Nutraland USA, Inc.",
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  [
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  [
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  [
   "Solarea Bio, Inc",
   1
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  [
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   1
  ],
  [
   "The Pharmaceutical Company LEK-AM Sp. Zoo., Przedsiebiorstwo Farmaceutyczne Lek-Am Sp. z o.o.",
   1
  ]
 ],
 "industry_open_drug_trials": [
  {
   "id": "NCT07829653",
   "url": "https://clinicaltrials.gov/study/NCT07829653",
   "sponsor": "Astellas Pharma Inc",
   "phase": "Phase 3",
   "title": "A Study to Confirm if Fezolinetant Helps to Reduce Hot Flashes in Indian Women Going Through Menopause",
   "registry": "ClinicalTrials.gov"
  },
  {
   "id": "NCT07794150",
   "url": "https://clinicaltrials.gov/study/NCT07794150",
   "sponsor": "Corium Innovations, Inc.",
   "phase": "Phase 1",
   "title": "A Study to Assess the Skin Irritation and Sensitization of Estradiol/Levonorgestrel TDS in Healthy Postmenopausal Subjects",
   "registry": "ClinicalTrials.gov"
  },
  {
   "id": "NCT07762287",
   "url": "https://clinicaltrials.gov/study/NCT07762287",
   "sponsor": "Bayer",
   "phase": "Phase 1",
   "title": "Evaluation of Possible Ways the Body May Process Two Different Forms of Elinzanetant in Healthy Study Participants",
   "registry": "ClinicalTrials.gov"
  },
  {
   "id": "NCT06644573",
   "url": "https://clinicaltrials.gov/study/NCT06644573",
   "sponsor": "Nyree Penn",
   "phase": "Phase 1",
   "title": "Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy\u2122 in Patients With Sleep Deprivation and Chronic Insomnia",
   "registry": "ClinicalTrials.gov"
  },
  {
   "id": "NCT07042516",
   "url": "https://clinicaltrials.gov/study/NCT07042516",
   "sponsor": "Tioga Pharmaceuticals",
   "phase": "Phase 2",
   "title": "Safety and Efficacy of Asimadoline (TP0052) in Patients With Vasomotor Symptoms (VMS).",
   "registry": "ClinicalTrials.gov"
  },
  {
   "id": "NCT07850050",
   "url": "https://clinicaltrials.gov/study/NCT07850050",
   "sponsor": "Boehringer Ingelheim",
   "phase": "Phase 3",
   "title": "SYNCHRONIZE\u00ae-HERA: A Study to Test Whether Survodutide Helps Women Who Are Living With Overweight or Obesity and Are Going Through or Have Finished Menopause, to Lose Weight",
   "registry": "ClinicalTrials.gov"
  },
  {
   "id": "2024-520234-30-00",
   "url": "https://euclinicaltrials.eu/ctis-public/view/2024-520234-30-00",
   "sponsor": "The Pharmaceutical Company LEK-AM Sp. Zoo., Przedsiebiorstwo Farmaceutyczne Lek-Am Sp. z o.o.",
   "phase": "Phase 3",
   "title": "A randomized, double-blind, placebo-controlled, multicenter study evaluating the effect of a 12-week\nDHEA combination of 20 mg and 2 mg prolonged-release melatonin on sleep quality and mood in\npostmenopausal women.",
   "registry": "EU CTIS"
  }
 ],
 "ongoing_ct": 326,
 "alltime_industry": [
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   "Bayer",
   34
  ],
  [
   "Novo Nordisk A/S",
   16
  ],
  [
   "Pfizer",
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  [
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   13
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  [
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   9
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  [
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   8
  ],
  [
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   8
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   7
  ],
  [
   "EndoCeutics Inc.",
   7
  ],
  [
   "Solvay Pharmaceuticals",
   6
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 ],
 "alltime_industry_total": 344,
 "by_treatment": [
  [
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   79
  ],
  [
   "Supplements & herbal",
   53
  ],
  [
   "Hormonal therapy",
   36
  ],
  [
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   33
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  [
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   25
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  [
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   15
  ],
  [
   "NK3 / NK1,3 antagonists (non-hormonal)",
   6
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  [
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   4
  ]
 ],
 "nk3_trials": [
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   "id": "NCT07606664",
   "url": "https://clinicaltrials.gov/study/NCT07606664",
   "sponsor": "Rebecca Thurston",
   "phase": "Phase 3",
   "title": "Fezolinetant and Vascular Health and Brain Health"
  },
  {
   "id": "NCT06975111",
   "url": "https://clinicaltrials.gov/study/NCT06975111",
   "sponsor": "University of Colorado, Denver",
   "phase": "Phase 2/3",
   "title": "Focusing on the Menopausal Transition to Improve Mid-Life Women's Health"
  },
  {
   "id": "NCT06917313",
   "url": "https://clinicaltrials.gov/study/NCT06917313",
   "sponsor": "Yale University",
   "phase": "Phase 2",
   "title": "FLASH-Breast: Evaluating the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy"
  },
  {
   "id": "NCT07077395",
   "url": "https://clinicaltrials.gov/study/NCT07077395",
   "sponsor": "Massachusetts General Hospital",
   "phase": "Phase 2",
   "title": "Finding Links Between Hot flASHes and CardioVascular Disease"
  },
  {
   "id": "NCT07829653",
   "url": "https://clinicaltrials.gov/study/NCT07829653",
   "sponsor": "Astellas Pharma Inc",
   "phase": "Phase 3",
   "title": "A Study to Confirm if Fezolinetant Helps to Reduce Hot Flashes in Indian Women Going Through Menopause"
  },
  {
   "id": "NCT07762287",
   "url": "https://clinicaltrials.gov/study/NCT07762287",
   "sponsor": "Bayer",
   "phase": "Phase 1",
   "title": "Evaluation of Possible Ways the Body May Process Two Different Forms of Elinzanetant in Healthy Study Participants"
  }
 ],
 "nk3_observational": [
  {
   "id": "NCT07602530",
   "url": "https://clinicaltrials.gov/study/NCT07602530",
   "sponsor": "Astellas Pharma Europe Ltd.",
   "title": "A Study in Canada to Follow Outcomes of Women in Menopause Treated With Fezolinetant for Hot Flashes, When Given in Clinical Practice"
  }
 ],
 "due_window": [
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  "2027-10-21"
 ],
 "due_total": 107,
 "due_interventional": 85,
 "due_industry": 18,
 "due_estimated": 107,
 "ongoing_past_due": 122,
 "due_key": [
  {
   "id": "NCT07342400",
   "url": "https://clinicaltrials.gov/study/NCT07342400",
   "sponsor": "Galderma R&D",
   "industry": true,
   "phase": "N/A (non-drug)",
   "status": "Recruiting",
   "primary_completion": "2026-11",
   "title": "A Clinical Study to Assess Histological Changes From Treatment of Poly L-lactic Acid Biostimulator on Women at Various Menopausal Stages"
  },
  {
   "id": "NCT07653620",
   "url": "https://clinicaltrials.gov/study/NCT07653620",
   "sponsor": "PepsiCo Global R&D",
   "industry": true,
   "phase": "N/A (non-drug)",
   "status": "Recruiting",
   "primary_completion": "2026-11",
   "title": "Hydration & Female Life Stages"
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  {
   "id": "NCT07393672",
   "url": "https://clinicaltrials.gov/study/NCT07393672",
   "sponsor": "Washington State University",
   "industry": false,
   "phase": "Phase 2",
   "status": "Recruiting",
   "primary_completion": "2026-11-10",
   "title": "Effects of Hemp-Derived Cannabinoids on Menopause Symptoms"
  },
  {
   "id": "NCT07861295",
   "url": "https://clinicaltrials.gov/study/NCT07861295",
   "sponsor": "Vidya USA Corporation",
   "industry": true,
   "phase": "N/A (non-drug)",
   "status": "Recruiting",
   "primary_completion": "2026-12-01",
   "title": "Satavari and Ashoka for Menopause (SAM) Study"
  },
  {
   "id": "NCT07611305",
   "url": "https://clinicaltrials.gov/study/NCT07611305",
   "sponsor": "Hofseth Biocare ASA",
   "industry": true,
   "phase": "N/A (non-drug)",
   "status": "Not yet recruiting",
   "primary_completion": "2026-12",
   "title": "ProGo Menopause Wellbeing Study"
  },
  {
   "id": "NCT06962345",
   "url": "https://clinicaltrials.gov/study/NCT06962345",
   "sponsor": "Mucosa Innovations, S.L.",
   "industry": true,
   "phase": "N/A (non-drug)",
   "status": "Recruiting",
   "primary_completion": "2026-12",
   "title": "Changes in the Impact of Genitourinary Syndrome of Menopause With a Novel Nonhormonal Vulvovaginal Gel Assessed by PROMs."
  },
  {
   "id": "NCT07413705",
   "url": "https://clinicaltrials.gov/study/NCT07413705",
   "sponsor": "BTL Industries Ltd.",
   "industry": true,
   "phase": "N/A (non-drug)",
   "status": "Recruiting",
   "primary_completion": "2026-12-11",
   "title": "BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and Postmenopausal Women"
  },
  {
   "id": "NCT06111209",
   "url": "https://clinicaltrials.gov/study/NCT06111209",
   "sponsor": "Brigham and Women's Hospital",
   "industry": false,
   "phase": "Phase 2",
   "status": "Active, not recruiting",
   "primary_completion": "2026-12-31",
   "title": "The Anabolic Effect of Testosterone on Pelvic Floor Muscles"
  },
  {
   "id": "NCT06611514",
   "url": "https://clinicaltrials.gov/study/NCT06611514",
   "sponsor": "European Institute of Oncology",
   "industry": false,
   "phase": "Phase 3",
   "status": "Not yet recruiting",
   "primary_completion": "2027-01-01",
   "title": "Effect of Intravaginal Prasterone on Symptoms of Genitourinary Syndrome of Menopause (GSM) in Women in Menopause With Previous Breast Cancer"
  },
  {
   "id": "NCT07880041",
   "url": "https://clinicaltrials.gov/study/NCT07880041",
   "sponsor": "LycoRed Ltd.",
   "industry": true,
   "phase": "N/A (non-drug)",
   "status": "Recruiting",
   "primary_completion": "2027-01",
   "title": "Evaluation of the Effect of a Nutraceutical Supplement on Hair Growth and Hair Quality in Premenopausal and Menopausal Women"
  },
  {
   "id": "NCT07538167",
   "url": "https://clinicaltrials.gov/study/NCT07538167",
   "sponsor": "Solarea Bio, Inc",
   "industry": true,
   "phase": "N/A (non-drug)",
   "status": "Not yet recruiting",
   "primary_completion": "2027-01",
   "title": "Food Trial Evaluating Fecal Abundance of SBD111 With Once-Daily Versus Twice-Daily Administration in Healthy Adults"
  },
  {
   "id": "NCT03916978",
   "url": "https://clinicaltrials.gov/study/NCT03916978",
   "sponsor": "Genesis Athens Clinic",
   "industry": false,
   "phase": "Phase 2/3",
   "status": "Recruiting",
   "primary_completion": "2027-01-30",
   "title": "Autologous PRP Intra Ovarian Infusion to Restore Ovarian Function in Menopausal Women"
  },
  {
   "id": "NCT04031456",
   "url": "https://clinicaltrials.gov/study/NCT04031456",
   "sponsor": "Genesis Athens Clinic",
   "industry": false,
   "phase": "Phase 2/3",
   "status": "Recruiting",
   "primary_completion": "2027-01-30",
   "title": "Autologous PRP Infusion May Restore Ovarian Function and May Promote Folliculogenesis in POI Patients"
  },
  {
   "id": "NCT05664477",
   "url": "https://clinicaltrials.gov/study/NCT05664477",
   "sponsor": "Roberta Brinton",
   "industry": false,
   "phase": "Phase 2",
   "status": "Active, not recruiting",
   "primary_completion": "2027-01-31",
   "title": "PhytoSERM to Prevent Menopause Associated Decline in Brain Metabolism and Cognition"
  },
  {
   "id": "NCT07118891",
   "url": "https://clinicaltrials.gov/study/NCT07118891",
   "sponsor": "AbCellera Biologics Inc.",
   "industry": true,
   "phase": "Phase 1/2",
   "status": "Active, not recruiting",
   "primary_completion": "2027-02",
   "title": "Study Evaluating ABCL635 for Vasomotor Symptoms of Menopause"
  },
  {
   "id": "NCT07762287",
   "url": "https://clinicaltrials.gov/study/NCT07762287",
   "sponsor": "Bayer",
   "industry": true,
   "phase": "Phase 1",
   "status": "Recruiting",
   "primary_completion": "2027-02-22",
   "title": "Evaluation of Possible Ways the Body May Process Two Different Forms of Elinzanetant in Healthy Study Participants"
  },
  {
   "id": "NCT07386249",
   "url": "https://clinicaltrials.gov/study/NCT07386249",
   "sponsor": "Seppic",
   "industry": true,
   "phase": "N/A (non-drug)",
   "status": "Recruiting",
   "primary_completion": "2027-03",
   "title": "Exploration of the Effect of a Wheat Polar Lipid Complex on Vaginal Dryness in Healthy Postmenopausal Women"
  },
  {
   "id": "NCT06530459",
   "url": "https://clinicaltrials.gov/study/NCT06530459",
   "sponsor": "National University Hospital, Singapore",
   "industry": false,
   "phase": "Phase 2/3",
   "status": "Recruiting",
   "primary_completion": "2027-04",
   "title": "The MUSE Study for Menopausal Arthralgia"
  },
  {
   "id": "NCT07548307",
   "url": "https://clinicaltrials.gov/study/NCT07548307",
   "sponsor": "Radicle Science",
   "industry": true,
   "phase": "N/A (non-drug)",
   "status": "Active, not recruiting",
   "primary_completion": "2027-04-07",
   "title": "Radicle Revive\u2122: A Study Assessing the Impact of Health and Wellness Products on Menopausal-Related Health Issues Associated Health Outcomes and Related Health Outcomes"
  },
  {
   "id": "NCT07663305",
   "url": "https://clinicaltrials.gov/study/NCT07663305",
   "sponsor": "Endo Health GmbH",
   "industry": true,
   "phase": "N/A (non-drug)",
   "status": "Recruiting",
   "primary_completion": "2027-05",
   "title": "Evaluation of a Mobile Menopause Application"
  },
  {
   "id": "NCT07794150",
   "url": "https://clinicaltrials.gov/study/NCT07794150",
   "sponsor": "Corium Innovations, Inc.",
   "industry": true,
   "phase": "Phase 1",
   "status": "Recruiting",
   "primary_completion": "2027-05-31",
   "title": "A Study to Assess the Skin Irritation and Sensitization of Estradiol/Levonorgestrel TDS in Healthy Postmenopausal Subjects"
  },
  {
   "id": "NCT01530373",
   "url": "https://clinicaltrials.gov/study/NCT01530373",
   "sponsor": "University of Arkansas",
   "industry": false,
   "phase": "Phase 2",
   "status": "Recruiting",
   "primary_completion": "2027-07",
   "title": "Solifenacin Compared to Clonidine for Reducing Hot Flashes Among Breast Cancer Patients"
  },
  {
   "id": "NCT07834463",
   "url": "https://clinicaltrials.gov/study/NCT07834463",
   "sponsor": "India Glycols Ltd",
   "industry": true,
   "phase": "N/A (non-drug)",
   "status": "Recruiting",
   "primary_completion": "2027-08-31",
   "title": "Randomized Evaluation of Natural Extract for Menopausal Wellness (RENEW)"
  },
  {
   "id": "NCT07824648",
   "url": "https://clinicaltrials.gov/study/NCT07824648",
   "sponsor": "SRI International",
   "industry": true,
   "phase": "N/A (non-drug)",
   "status": "Recruiting",
   "primary_completion": "2027-09-15",
   "title": "Thermoregulatory Physiology of Menopausal Hot Flashes"
  }
 ]
}